About Cros Proviedon
Cros Proviedon
Crospovidone. Crospovidone is a water insoluble synthetic cross-linked PVP. Crospovidone acts via different mechanisms including the swelling, and wicking followed by secondary swelling as proposed by Kornblum & Stoopak (1973).
Exceptional Superdisintegrant PerformanceCros Proviedon delivers reliable superdisintegrant action due to its high purity and optimal particle size, easily passing through a #100 mesh. Its unique crosslinked structure promotes rapid water absorption, resulting in efficient tablet disintegration and enhanced bioavailability for oral pharmaceuticals.
Stringent Quality and CompatibilityManufactured under strict USP/NF standards, Cros Proviedon ensures safety with heavy metals below 10 ppm and full compliance with microbial limits. It is compatible with a wide range of pharmaceutical actives, making it an essential excipient in both standard and innovative formulation development.
Flexible Storage and Packaging SolutionsTo preserve quality, Cros Proviedon should be stored in a cool, dry environment and is available in sealed 25 kg drums or as required by the customer. With a three-year shelf life under proper storage conditions, it provides reliable supply for manufacturers and traders across India.
FAQ's of Cros Proviedon:
Q: How is Cros Proviedon typically used in the pharmaceutical industry?
A: Cros Proviedon is primarily employed as a superdisintegrant in solid dosage pharmaceutical formulations, such as tablets and capsules, to promote rapid disintegration and improve the release and absorption of active ingredients.
Q: What benefits does Cros Proviedon offer as a tablet disintegrant?
A: This excipient enhances the disintegration and dissolution rate of oral solid dosage forms, ensuring faster onset of therapeutic action and improved bioavailability of pharmaceutical actives.
Q: What is the recommended process for storing Cros Proviedon?
A: Cros Proviedon should be stored in tightly closed containers in a cool, dry place, away from moisture and direct sunlight, to maintain its efficacy and shelf life.
Q: What is the usage level of Cros Proviedon in a typical formulation?
A: The optimal usage level varies depending on the formulation, but it is usually incorporated at 2-5% by weight of the total tablet or capsule content, ensuring effective disintegration.
Q: When should Cros Proviedon be added during the manufacturing process?
A: It can be added either intragranularly during granulation or extragranularly to the blend prior to compression, depending on the desired disintegration profile and formulation requirements.
Q: Where can Cros Proviedon be supplied from, and what packing options are available?
A: Cros Proviedon is available from suppliers and traders in India, typically packed in 25 kg drums or customized packages to meet customer specifications.
Q: Is Cros Proviedon safe and non-toxic for use in pharmaceuticals?
A: Yes, Cros Proviedon is non-toxic, odorless, tasteless, and complies with USP/NF standards, making it safe for use in pharmaceutical products.